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Successful laboratory test of photoswitchable anti-tumor agent
Photoswitchable agents might reduce side effects of a chemotherapy. So far, photodynamic therapies have been dependent on oxygen in the tissue. But hardly any oxygen exists in malignant, rapidly...
View ArticleLife-preserver microbubbles float tumor cells for analysis
A University of Colorado Cancer Center study presented at the American Association for Cancer Research Annual Meeting 2016 demonstrates the use of gas microbubbles to selectively attach to and float...
View ArticleModel of tumor spreading may help doctors pinpoint best treatment
Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors. But what if before initiating treatment, they could go a step further and use...
View ArticleNovel gene variants identified in male breast cancer
Male breast cancer (MBC) is a very rare tumor type, occurring in just 1% of all breast cancer cases, and the underlying genetic causes and treatment of MBC is not well understood. In a paper...
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From tamoxifen to dendrogenin A: Discovery of a mammalian tumor suppressor...
Researchers from the Cancer Research Center of Toulouse have conducted the first comprehensive review on dendrogenin A (DDA). DDA is a steroidal alkaloid arising from cholesterol and histamine...
View ArticleChemotherapy can cause tumor evolution
Russian scientists have found that neoadjuvant chemotherapy in patients with breast cancer can stimulate evolution of the tumor. The research was conducted by Nicholay Litvyakov, D.Sc. at Cancer...
View ArticleTurncoat protein regulates sensitivity of breast cancer cells to drug
A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a common...
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Research team identifies structure of tumor-suppressing protein
An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN....
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Watching a tumour grow in real-time
The ability to visualize and characterize the composition of a tumour in detail during its development can provide valuable insights in order to target appropriate therapeutics. Researchers from the...
View ArticleHigher Tumor Rates by Exposure to Electromagnetic Fields
Electromagnetic fields stimulate the growth of tumors in mice. This is the result of a new study by researchers from Jacobs University in Bremen, Germany, which was commissioned by the Federal Office...
View ArticleCrown Bioscience Acquires Molecular Response’s Patient Derived Xenograft...
Crown Bioscience, Inc. has announced the acquisition of Molecular Response’s PDX models and PDX service operations. The acquisition reinforces Crown’s on-going strategy to be the leading global...
View ArticleOncoethix starts Phase 1b Trials of OTX015 in the Treatment of Advanced Solid...
Oncoethix announced that the first patient has been enrolled in an international, open-label, non-randomized, multicenter Phase 1b trial of OTX015 in advanced solid tumors. The trial will be...
View ArticleStudy identifying cell of origin for large, disfiguring nerve tumors lays...
UT Southwestern Medical Center researchers have determined the specific type of cell that gives rise to large, disfiguring tumors called plexiform neurofibromas, a finding that could lead to new...
View ArticleMerck Serono Awards €1 Million to the Winners of the first Grant for Oncology...
Merck Serono, the biopharmaceutical division of Merck, announced the winners of the first Grant for Oncology Innovation (GOI), who will receive grants totaling €1 million. The 2014 winners were...
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Male infertility: It's all about the package
Infertility is generally thought of as a woman's problem. In fact, more than 3 million men across America also experience it. Today, researchers from Cold Spring Harbor Laboratory (CSHL) describe a...
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Two-lock box delivers cancer therapy
Rice University scientists have designed a tunable virus that works like a safe deposit box. It takes two keys to open it and release its therapeutic cargo. The Rice lab of bioengineer Junghae Suh has...
View ArticleEmerging psoriasis therapies go head-to-head with marketed drugs
The market for moderate-to-severe plaque psoriasis therapeutics is becoming increasingly competitive with the imminent arrival of three promising new drug classes: interleukin-17(IL-17) inhibitors, a...
View ArticleNano shake-up
Significant advances have been made in chemotherapy over the past decade, but targeting drugs to cancer cells while avoiding healthy tissues continues to be a major challenge. Nanotechnology has...
View ArticleKill resistant tumor cells
Researchers from the University of Pittsburgh Cancer Institute (UPCI), a partner with UPMC CancerCenter, have found that an agent that inhibits mitochondrial division can overcome tumor cell...
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Protein key to cell motility
"Cell movement is the basic recipe of life, and all cells have the capacity to move," says Roberto Dominguez, PhD, professor of Physiology at the Perelman School of Medicine, University of...
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